Job description
Job Summary - Cancer Molecular Biology & Proteomics (Kim lab, UT Health San Antonio, TX)
The Department of Biochemistry and Structural Biology at UT Health San Antonio is recruiting research specialists to join the laboratory of Minkyu Kim, PhD.
This position will provide an excellent opportunity to learn a number of valuable, cutting-edge techniques in quantitative proteomics and systems biology as well as cell and molecular biology, while working with a dynamic and interdisciplinary research team at UT Health San Antonio, TX.
This appointment will focus on how the DNA damage response (DDR) signaling is regulated as DNA repair initiates, proceeds, and terminates. Temporal proteomic changes during the DDR will be measured by performing global proteomics (abundance and PTM) and protein-protein interactome analysis using affinity purifications and proximity labeling Mass Spectrometry. The scientist in this position will also characterize newly identified DDR regulators for their roles in DNA repair and replication, signaling, and cell cycle progression.
Job Duties:
- Experience in essential molecular biology and biochemistry techniques (PCR, cloning, western blot).
- Experience in cell/tissue culture and cell-based assays.
- Ability to work independently and meet deadlines; recognize and resolve problems while maintaining a high level of organization.
- Effective verbal and written communication skills to interface with the team to review and analyze the results.
- Demonstrated experience in Microsoft Word, Excel, and PowerPoint.
Education:
Bachelor’s degree or master’s degree in a related field
Experience:
Four (4) years of experience is required.
Preferred Qualifications:
- Experience generating new cell lines by CRISPR and other methods and characterizing them.
- Experience in sample preparation for mass spectrometry and data analysis by R.
- Experience in protein purification.
- Experience in fluorescence microscopy and/or flow cytometry
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