Job description
At Eisai, satisfying unmet medical needs and increasing the benefits healthcare provides to patients, their families, and caregivers is Eisai’s human health care (hhc) mission. We’re a growing pharmaceutical company that is breaking through in neurology and oncology, with a strong emphasis on research and development. Our history includes the development of many innovative medicines, notably the discovery of the world's most widely-used treatment for Alzheimer’s disease. As we continue to expand, we are seeking highly-motivated individuals who want to work in a fast-paced environment and make a difference. If this is your profile, we want to hear from you.
Scientist II, Precision Chemistry
General Summary:
The Eisai Center for Genetics Guided Dementia Discovery (G2D2) is an industry-unique drug discovery biotech with a diverse group of passionate, dedicated and collaborative scientists committed to helping eradicate Alzheimer’s disease and other dementias. Recognizing the potential for human genetics, data sciences and precision chemistry to disrupt the drug discovery paradigm, Eisai established G2D2 to accelerate the discovery of innovative therapeutics. G2D2 is committed to accelerating drug discovery premised upon robust insights from human biology, and driving multi-disciplinary team-based progress towards addressing real unmet patient needs.
At G2D2, we focus not only on how such data help identify and validate therapeutic targets, but also to guide novel approaches to drug such targets and match them to the right patient at the right time. Our precision chemistry strategy - in the context of insights from human genetics - is uniquely positioned to deliver tailor-designed small molecule, anti-sense oligo-nucleotide, and other solutions for targeted therapeutics.
Our new cutting-edge 50,000-square-foot facility is strategically located in Cambridge, MA, to accelerate collaborations with leading research institutes in this world-class biotech hub. Our facility has been designed around a novel open-lab concept, enabling chemists, biologists, automation and other scientists to work together in a single common and integrated lab space. Our labs include state-of-the-art capabilities in medicinal and process chemistry, in-vitro and in-vivo biology, microscopy, chemical and structural biology, automation and screening, and several other discovery technologies and platforms.
You will join a highly interactive and collaborative team spanning a broad range of drug discovery capabilities. We highly value both internal and external collaborations, and you will become involved in flexible research models with a range of external scientific partners to accelerate delivery of innovative medicines. As an Eisai employee you will spend at least 1% of your working time with patients and families to ensure that the innovation you drive is based on an understanding of their real needs.
More information about G2D2 is provided here (
http://eisai.mediaroom.com/2018-06-12-Eisai-Inc-to-Launch-Center-for-Genetics-Guided-Dementia-Discovery-in-Cambridge-Massachusetts
) and here (
https://us.eisai.com/research/g2d2
), and about Eisai's Neurology strategy and pipeline are provided here (
https://www.eisai.com/index.html
).
We are seeking to fill a new Scientist II position in the Precision Chemistry department of our Discovery Evidence Generation group. The successful candidate is expected to work independently to identify and solve project related problems. This position requires outstanding demonstrated expertise in organic synthesis. Additionally, demonstrated ability to apply expertise in organic chemistry to address biological problems is preferred. This position works closely with computational scientists, structural and cell biologists, and assay scientists in a project setting. Strong communication skills are required, and a broad understanding of the drug discovery process is a plus.
Primary responsibilities:
- Design and synthesis of compounds to test biological hypotheses
- Identify and solve significant problems related to project
- Design and execute experiments with a high level of independence
- Analyze, interpret, and deliver results in timely fashion
- Justify, propose, assess and lead the introduction of new technologies and/or projects
- Drive collaboration across research groups and communicate results to colleagues within project context
- Communicate effectively with internal and external collaborators to achieve company objectives
- Work effectively in multi-disciplinary team environment
Qualifications/Skills:
- PhD in relevant scientific field strongly preferred, but combination of equivalent experience and education may be considered in lieu of PhD
- Up-to-date knowledge of synthetic organic chemistry
- Experience in synthetic route design and synthesis of complex molecules
- Proficient in experimental design and laboratory equipment
Eisai requires all new hires to be fully vaccinated against COVID-19 and provide valid proof of vaccination as of their start date, to the extent permitted under applicable law. This requirement is a condition of employment at Eisai, and it applies regardless of whether the position is located at an Eisai site, field based or is fully remote. If you are unable to receive the vaccine for qualifying medical reasons (including pregnancy-related), or religious reasons (sincerely held religious beliefs), you will have an opportunity to request a reasonable accommodation.
Eisai is an equal opportunity employer and as such, is committed in policy and in practice to recruit, hire, train, and promote in all job qualifications without regard to race, color, religion, gender, age, national origin, citizenship status, marital status, sexual orientation, gender identity, disability or veteran status. Similarly, considering the need for reasonable accommodations, Eisai prohibits discrimination against persons because of disability, including disabled veterans.
Eisai Inc. participates in E-Verify. E-Verify is an Internet based system operated by the Department of Homeland Security in partnership with the Social Security Administration that allows participating employers to electronically verify the employment eligibility of all new hires in the United States. Please click on the following link for more information:
Right To Work
E-Verify Participation
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