Job description
Working with Us
Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible.
Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us.
When you join BMS, you are joining a diverse, high-achieving team united by a common mission.
The Clinical Pharmacology, Pharmacometrics, Disposition and Bioanalysis (CPP-DB) team at BMS is responsible for the pharmacology and pharmacometric support for all pipeline assets throughout the clinical development lifecycle. Composed of pharmacologists, pharmacometricians, and mechanistic modelers, this group oversees the pharmacokinetic evaluation, pharmacometric exposure-response evaluation, quantitative systems pharmacology modeling, physiologically based pharmacokinetic modeling and model based meta-analysis of assets covering all platforms of therapies, including small molecules, traditional and complex biologics and next gen cell therapies. All therapeutic areas are supported. The CP&P team interacts with discovery and translational scientists, project leadership, early development, late development and commercial colleagues to optimize dosing, formulation, delivery and combination strategies to enable faster and more effective drug development informed by core scientific principals and data.
Here, you’ll get the chance to grow and thrive through opportunities that are uncommon in scale and scope. You’ll pursue innovative ideas while advancing professionally alongside some of the brightest minds in biopharma.
Position Summary
The Toxicokinetic (TK) Scientist in the Clinical Pharmacology, Pharmacometrics, Disposition and Bioanalysis (CPP-DB) department within Precision Discovery and Translational Sciences will provide pharmacokinetic/toxicokinetic (PK/TK) support to toxicology studies [ie, exploratory and definitive/Good Laboratory Practice (GLP)] and execute PK/TK strategies to support the development of small molecules and biologics.
Key Responsibilities
Serve as a contributing scientist to toxicology studies and execute all phases/aspects of the toxicokinetic evaluation with minimum supervision. Essential duties include, but not limited to the following: provide TK study design, calculate PK/TK parameters, provide PK/TK data interpretation, and write reports that meet high standards in accordance with external and internal regulations.
Serve as a key contact for all TK-related issues pertinent to the development of assigned drug candidates and closely interact with study directors, project representatives, bioanalytical scientists, and other relevant functional areas.
Deliver high quality scientific results according to agreed timeline for several concurrent studies.
Effectively communicate study results at internal meetings, as appropriate.
Use judgment and knowledge where appropriate to influence project team decision making
Create an atmosphere of scientific excellence, open communication, and creativity in order to maximize productivity.
Ensure compliance with GLP, SOPs, and study protocols.
Ensure compliance with all company/departmental policies, as well as other federal, state and corporate policies and guidelines particularly those relating to animal welfare and employee safety and health.
Monitor the quality of toxicokinetic reports and ensure the efficiency and effectiveness of TK data/report generation process.
Basic Qualifications
Bachelor’s Degree and 5+ years of academic and / or industry experience OR
Master’s Degree and 3+ years of academic and / or industry experience OR
Ph.D. or equivalent advanced degree in the Life Sciences
Preferred Qualifications & Experience
B.S. or M.S. in related field of science, with minimum of 3 or 5-years relevant experience (M.S. or B.S., respectively) in pharmaceutical or biotech industry, preferably in pre-clinical/clinical research.
Knowledge of pharmacokinetics and drug metabolism is required.
Experience in pharmacokinetics and ability to perform PK and TK calculations including data interpretation are expected; experience with Phoenix/WinNonlin and Watson LIMS is a plus.
A basic understanding of the principles of GLP is preferred but not required.
Must demonstrate strong work ethics, problem solving skills, ability to work independently, and ability to manage multiple projects at once.
Excellent verbal and written communication skills, organizational skills, and attention to detail.
Proficient in Microsoft Word and Excel.
If you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.
Uniquely Interesting Work, Life-changing Careers
With a single vision as inspiring as “Transforming patients’ lives through science™ ”, every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in an inclusive culture, promoting diversity in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.
On-site Protocol
Physical presence at the BMS worksite or physical presence in the field is a necessary job function of this role, which the Company deems critical to collaboration, innovation, productivity, employee well-being and engagement, and it enhances the Company culture.
BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to adastaffingsupport@bms.com. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.
BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.
BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.
Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.
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